Police have identified the three victims killed in the deadly crash that happened on I-75 southbound at I-94 in Detroit early Wednesday morning.
The southbound lanes of I-75 were shut down for hours on Wednesday.
Michigan State Police say a wrong-way driver caused the crash.
That driver has been identified as 34-year-old Leanna Monica Custard of New Baltimore. Police say she drove her Chevy Malibu the wrong way on I-75 after leaving Greektown Casino.
The other two people killed were in a 2000 Oldsmobile Silhouette. They have been identified as 23-year-old Karl Louis Hawkins of Pontiac and 21-year-old Elijah Duane Holden of Auburn Hills.
Police also say two people were taken to the hospital with injuries. They have been identified as a 22-year-old and a 24-year-old, both from Pontiac. They both suffered critical injuries.
Heading downtown? Avoid I-75 SB!! It will be closed for HOURS due to a crash.
Try I-94, M-10 or Woodward instead @wxyzdetroit https://t.co/KW9HqPrNfc— Jennifer Ann Wilson (@JennaWils) January 4, 2017
The investigation is ongoing.