The FBI, Michigan State Police, and Detroit Police spent several hours Thursday at a home on Electric Street on the city's southwest side.
At least three women were rescued this afternoon, after being held against their will.
Sources say a woman ran away from the house, calling 911.
When authorities arrived, they rescued two other women.
We've learned two other juveniles were believed to be in the house at the time, possibly 15 and 16-years-old, but left before police got there.
A 69-year-old man was taken away in police custody.
Neighbor Olive Wise told us, "Wow! Too much for words, too much for words."
Another neighbor who did not want to be identified says, "It's absolutely horrible. There are children that play on this street. It's scary."
She went on to say it's time move.
Sources tell 7 Action News it could be connected to sex trafficking, also an organized prostitution ring in Port Huron. The women rescued were in their 30s and 40s.
Last week, we told you about what happened in Port Huron. The neighborhood enforcement team set up stings at hotels and houses, arresting more than 20.
The FBI is not commenting about this on-going investigation, only saying they were called here by Detroit Police.
Sources say two women were taken to the hospital to be checked out, showing obvious signs of abuse.