Detroit City FC will take on Indy Eleven, also of the USL Championship, in the round of 16 in the Lamar Hunt U.S. Open Cup.
Le Rouge advanced to the round of 16 after beating the MLS Houston Dynamo on Tuesday night in penalty kicks.
Indy beat San Antonio FC 2-0 in their round of 32 matchup.
Detroit will travel to Indianapolis for the matchup, where they have already won this year.
In March, Detroit beat Indy 2-1 on the road at the beginning of the season with goals from Ali Coote and Maxi Rodgriguez.
If Detroit wins, they'll advance to the round of 8 where they are likely to face another MLS team.
